Rationale engineering generates a compact new tool for gene therapy
Researchers redesign a compact RNA-guided enzyme from bacteria, making it an efficient editor of human DNA.
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Genetic engineering
The programmable proteins are compact, modular, and can be directed to modify DNA in human cells.
Read MoreA causal theory for studying the cause-and-effect relationships of genes
By sidestepping the need for costly interventions, a new method could potentially reveal gene regulatory programs, paving the way for targeted treatments.
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